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Monoclonal antibodies are antibody molecules having homogeneous structure and known specificity. This book provides a basic and over all idea of research carried out in the field of monoclonals for the past three decades. This book discusses in detail the production of monoclonalanti bodies, the techniques used to make human monoclonals, the wide applications of monoclonals in various fields like medical,environmental, industrial and research and the FDA-approvedm onoclonal drugs with respect to their nature, their modes of action, and the experiments undertaken during their clinical trials, with appropriate diagrams and graphic illustrations. The book also discusses the research undertaken by various biotech companies, patents applied, and the present and future status of monoclonals in the drug market.